There were cured jaundice, weight loss, liver enlargement, microscopy (i.e., piecemeal necrosis, focal lytic necrosis, apoptosis and focal inflammation, and disturbed cell proliferation (Ki-67-staining), cytoskeletal structure in the hepatic stellate cell (-SMA staining), collagen presentation (Mallory staining), and biochemistry presentation (Sever et al., 2019), and counteracted the increased NOS3 expression, interleukin (IL)-6, tumor necrosis factor (TNF)-, and IL-1 levels
The authors also thank Susanne Meza-Keuthen for carefully reviewing the manuscript
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Fibrometers (ie, liver-fibrosis-specific blood panels), which combine some of these markers with other liver-specific markers, are also available (Castera 2012)