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10.1007/s00253-018-9155-6 231

This is the only growth hormone peptide with FDA approval and Phase III randomized trial data specifically demonstrating selective visceral fat reduction

In summary, long-acting GLP-1R agonists primarily reach the circumventricular organs of the hindbrain and food-intake controlling centers of the hypothalamus

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doi: 10.2337/db14-1577