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More affordable options include Phentermine/topiramate branded as Qsymia at $223.44, and Bupropion/naltrexone known as Contrave at $175

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Leptin gene mutations are now treated by administration of the recombinant form of human leptin, metreleptin, in subcutaneous form

However, due to high potency, multiple or prolonged doses may be required to fully reverse an overdose

J Clin Invest 115 : 35643572 Date Y et al

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