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It has not progressed to extensive clinical trials, meaning its human safety and efficacy profile is not established it remains strictly a preclinical research compound

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The Drug Enforcement Administration (DEA) has oversight for any controlled substances used in the preparation of compounded medications including hydrocodone, amphetamines

for generalised pruritus, non-sedating antihistamines such as cetirizine or loratadine and unperfumed emollients may provide relief