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"I tend to go 45 weeks with losses and then have a bounce back week." Island303 Others describe longer pauses: "I stayed the same/gained weight for around 15 days then dropped around 2lb below my last lowest." N335H Even during a plateau, progress may be happening internally: "Stalls happen, even on wegovy." GelatinousFart This is why scale trends - not individual days - tell the truest story

Remove the needle when done

Hdac1 and Hdac2 act redundantly to control p63 and p53 functions in epidermal progenitor cells

The oral GLP-1 era has officially begun

GLP-1 (glucagon-like peptide-1) is a natural hormone that helps regulate appetite and food intake

When stress becomes chronic, the same signal tends to push the brain toward fast calories, larger portions, and reward-driven eating, which is where cortisol appetite control tends to break down