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PubMed Central, Weghuber, Daniel, et al

Erythritol is 6070% as sweet as sucrose -table sugar- yet it is almost noncaloric, does not affect blood sugar, does not cause tooth decay, and is partially absorbed by the body, excreted in urine and feces

Osmolality is approximately 305 mOsm

Kynurenine is predominantly metabolized to the N -methyl-d-aspartate (NMDA) receptor agonist quinolinic acid (QUIN) in the inflammatory state, contributing to the accumulation of glutamate in the extracellular space, leading to changes in network connectivity associated with depression, fatigue and cognitive impairment

Originally developed to treat type 2 diabetes by regulating blood sugar levels, GLP-1 medications have demonstrated a remarkable ability to induce weight loss as well

The PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetes trial is a multicenter study evaluating GLP-1 RAs versus SGLT2i for both primary and secondary prevention of ASCVD in patients with T2DM [62]