It runs roughly as follows
It follows with increased melanin production that leads to hyperpigmentation and reduced effect of glutathione
D., Cai, X., Ma, C., Wang, Y., Dai, A., Zhou, Y., Sun, W., Zhao, F., Zhao, S., Jiang, H., Jiang, Y., Yang, D., Eric Xu, H., Wang, M
A healthy level of Glutathione is crucial because the degenerative process of autoimmune disease destroys the mitochondria in affected cells, such as thyroid tissue in Hashimotos
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In PTSD mice models, trauma exposure increased tyrosine hydroxylase expression (the rate-limiting enzyme in catecholamine biosynthesis), elevating stress hormones epinephrine and norepinephrine in serum and colon, which upregulated claudin-2 expression, confirming gut barrier dysfunction (Yadav et al., 2023)