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P-gp is an ATP-dependent efflux pump located in the cell membrane that, among other drugs, transports Tac back into the intestinal lumen

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Dbrowska G, Kata A, Goc A, Szechyska-Hebda M, Skrzypek E

However, the lack of significant improvement in whole-blood glutathione raises concerns about whether glutathione is being effectively absorbed at the intracellular level, where it is most needed