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Major adverse cardiovascular events (MACE)including cardiovascular death, non-fatal myocardial infarction, and non-fatal strokewere not increased with Zepbound treatment, though the trial was not specifically powered to evaluate cardiovascular outcomes

The evidence is not settled and appears to be influenced by an individual person microbiome and long term diet patterns

doi: 10.3389/FENDO.2023.1215356 94 YounesSTMaedaKJSasserJRyanMJ

So your mouth gets drier, and your teeth start to get more brittle

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