[DOI] [PMC free article] [PubMed] [Google Scholar] 91.Shi C., Zhao L., Zhu B., Li Q., Yew D.T., Yao Z., Xu J
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and patients with glutathione-S-transferase M1 (proinflammatory-cytokine producer macrophages) null and M1 and T1 (Type 1 helper CD4 + lymphocytes) double null polymorphisms had increased mortality suggesting that antioxidant therapy becomes fundamental for those patients (109)
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Meanwhile, an elevated status in reduced glutathione has been found to be linked to a number of processes associated with longevity, with an apparent connection between glutathione and the activity of telomerase, an enzyme which influences cell survival by maintaining telomeres