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Across tested doses and routes, the elimination half-life remained under 30 minutes, with full plasma clearance occurring within 24 hours

Open Biol (2015) 5(9):1500933

As key regulators of intestinal homeostasis, normal microbiota maintain the integrity of the intestinal epithelial barrier and immune tolerance through their metabolic products

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The treatment of cobalamin-related remethylation disorders aims to reduce tHcy andin combined defectsto normalize MMA in order to improve clinical features [2]

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