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When pitting edema is present, venous insufficiency should be investigated in women with lipedema by a venous duplex ultrasound of the legs

doi: 10.5604/17322693.951633 38 KochetovGASolovjevaON

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Finally, B1 cells need to migrate to niches that support antibody production in order to increase secretion of IgM OSE

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The mild elevation of -BB, coupled with a conserved amino acid change, suggests that D72G is a hypomorphic, milder variant resulting in a quantifiable metabolic phenotype where small deviations in -BB levels are metabolically tolerable in C