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Starting GLP-1 treatment can feel like a positive step, but it often comes with a learning curve

But as GLP-1 use rapidly expands at the same time access to primary care is shrinking, it is reasonable to worry whether overstretched clinicians will be able to adapt or whether many people will still be left to navigate their weight-loss journey on their own

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That makes it cheaper to manufacture and avoids some of the drug interaction concerns

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Furthermore, the Endocrine Societys obesity guideline recommends that patients with obesity in the absence of diabetes should discontinue weight-loss medications if safety or tolerability issues arise, and consider other therapeutic options