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NCOA4, Nuclear receptor coactivator 4

Abstract Glutathione S -transferases (GSTs) are phase II drug detoxifying enzymes that play an essential role in the maintenance of cell integrity and protection against DNA damage by catalyzing the conjugation of glutathione to a wide variety of exo- and endogenous electrophilic substrates

NAC supplements N-acetyl cysteine (NAC) is another amino acid and critical antioxidant

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In normal physiology, ammonium derived from deamination is transported as glutamine or alanine to hepatocyte mitochondria, where it undergoes enzymatic conversion to urea via the urea cycle (Details in Table 1 )

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