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Clinically, elevated levels of endogenous GLP-1 have been observed in patients with sepsis (6.35-fold increase), end-stage renal disease (4.46-fold), and burns (2.96-fold), indicating a common physiological response to critical illness ( Despite these observations, exogenous GLP-1RAs appear to exert beneficial effects

Pratley R, Amod A, Hoff ST, et al

When food remains in the stomach longer than usual, it can lead to feelings of fullness, abdominal distension, and bloating

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Rubio, G