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The activation of GLP-1R promotes the release of -endorphins, which mediate analgesic effects through receptors at the neuronal level [39, 42]
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Conclusion APAP ingestion and subsequent hepatotoxicity is a critical problem that continues to plague individuals across the world, due to the cheap cost of APAP contributing to its being a ubiquitous analgesic and anti-pyretic drug available through consumer pharmacies and as prescription-only medication formulations
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Samms RJ, Christe ME, Collins KA, Pirro V, Droz BA, Holland AK, et al