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Do not mix it with other strong things in the beginning

The Trustees found that: Utilization of these medications has been very high Some utilization may not align with FDA guidelines Costs to the Fund exceeded $5 million in 2025 To help ensure appropriate use and manage Plan costs, the Trustees adopted a prior authorization requirement

Gradually lowering the dose and having a maintenance plan in place can help reduce the risk of regain

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Blood tests and doctor visits help see if the dose is right

PMID: 35105939 Immunity Multiomics analyses reveal a critical role of selenium in controlling T cell differentiation in Crohn's disease