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Seven meta-analyses investigated the effect on LDL, 57.14% of them observed significant reduction with MD from 3.55 to 0.29 (14, 28, 30, 32)

The process of the removal of old erythrocytes from the circulation is also known as senescence, and similar to eryptosis, this process may be preferentially executed due to oxidative stress, hyperosmolarity, and energy depletion [24, 134]