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This mechanism focuses on the degradation and recycling of cellular components (107, 114, 115)

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doi: 10.1039/9781847558428-00003 58 LiD.LiZ.WangX.WangL.KhosoA

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A concrete example that clarifies this boundary is gastrin: multiple adequately powered human trials demonstrated that gastrin-based therapies failed to preserve beta-cell function in type 2 diabetes, and development was largely discontinued by approximately 2010