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Both medications are contraindicated in people with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)

doi: 10.1016/j.fbio.2018.09.003 346 SilvaVIgrejasGFalcoVSantosTPTorresCOliveiraAMet al

At the same time, abrupt rises in ALT or AST should prompt symptom-driven evaluation, as rare adverse reactions can occur

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Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist administered subcutaneously for type 2 diabetes management (Ozempic) and chronic weight management (Wegovy)