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Physicians should avoid prescribing it to: Patients with a history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN2). Individuals with severe gastrointestinal conditions, such as gastroparesis. Patients with a known allergy to GLP-1 receptor agonists. Pregnant or breastfeeding women, unless approved by a physician

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A major signal of this trend moving into Europe came in June 2025, when Hims & Hers announced its acquisition of Zava, a European telehealth platform with operations in the UK, Germany, France, and Ireland