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Injecting air into the BAC water vial before withdrawing solvent equalizes pressure, making drawing easier and reducing vacuum resistance on the plunger

Importantly, food intake remained unchanged in treated animals, suggesting the compound's effects relate to energy expenditure pathways rather than appetite

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8.7 Hepatic Impairment No dosage adjustment of MOUNJARO is recommended for patients with hepatic impairment

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However, a significant level of heterogeneity was observed (I=80% for mortality, 73% for infection)