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GLP-1 binding to GLP-1R promotes -cell glucose metabolism through mTOR-dependent HIF-1 activation

Many will remember the widely-circulated food pyramid with whole grain carbohydrates at its base, posted seemingly ubiquitously in the 1980s and 1990s

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Now, researchers are looking at pairing these glucagon-like peptide 1 ( GLP 1 ) agonistsand dual GLP-1/ glucose-dependent insulinotropic polypeptide (GIP) receptor agonists with drugs that treat inflammatory diseases such as psoriasis to see if the combination boosts effectiveness