The tradeoff between tolerability and rate of weight loss is a personal decision, but staying on a tolerable dose long-term is almost always better than cycling on and off the maximum dose
Moreover, ferroptosis induction in tumor cells is thought to be related to the release of prostaglandin E2 (PGE2), which facilities the evasion from immune surveillance (Yang et al., 2014)
Nat Commun 10 , 924 (2019)
Adding exogenous glutathione to a drug that already modulates oxidative stress raises a conceptual question: could the combined antioxidant load suppress reactive oxygen species (ROS) to a degree that interferes with beneficial ROS signaling
What If I Want Faster Absorption But Don't Want IM Pain
Irwin N, Hunter K, Frizzell N, Flatt PR (2009) Antidiabetic effects of subchronic activation of the GIP receptor alone and in combination with background exendin-4 therapy in high fat fed mice