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These metabolites, though more water-soluble, are less bioactive than the parent compound ( The lipophilic nature of curcumin significantly limits its absorption through the gastrointestinal tract

doi: 10.1136/bmj.2.6198.1097 [DOI] [PMC free article] [PubMed] [Google Scholar] 10.Bavarsad Shahripour R, Harrigan MR, Alexandrov AV

It was also found to reduce elevated liver enzymes (ALT, AST) and reduce the progression of fibrosis in NAFLD and alcoholic liver disease (ALD)

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4.2 Cardiovascular and autonomic dysfunction Autonomic dysfunction is a hallmark nonmotor feature of PD and includes: Orthostatic hypotension (in up to 3040%)

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