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The peptide backbone optimization strategies employed in Retatrutide development focus on enhancing proteolytic stability, improving pharmacokinetic properties, and maintaining receptor selectivity across multiple targets [1] [2]

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Participants also had a decrease in HbA1c from 6.9% at baseline to 6.3% at follow-up ( P = .001)

A pharmaceutical patent, at its core, grants a 20-year monopoly in exchange for public disclosure of an invention