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Beyond body weight reduction, GLP-1 RAs have anti-inflammatory and antioxidative effects, with plaque stabilisation associated with a specific reduction in cardiovascular events and, in particular, ischaemic events, stroke and acute MI

Iacobellis et al

Weyer C, Gottlieb A, Kim DD, et al

In this plan, the focus has shifted from a pure glucocentric approach towards a holistic approach, with a preferred use of agents with proven cardiorenal superiority (11)

The pills are priced at $149 a month for the lowest doses if patients pay out of pocket, through a deal struck with the Trump administration in November through its TrumpRx drug pricing initiative