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When exposed to electrophiles (i.e., certain antioxidants) or oxidative stress, Keap1 is inactivated

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The natural product domain seeker NaPDoS: a phylogeny based bioinformatic tool to classify secondary metabolite gene diversity

Given that cancer cells are much more dependent on glutamine than immune cells and that V-9302 does not impair CD8(+) T-cell viability and activation 83 , pharmacological inhibitors of SLC1A5 might have high therapeutic potential

Peng, M., Cai, Y., Fang, X

This variant is more difficult to define because it overlaps with the signs of aging