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In pharmacokinetic studies, patients with moderate and severe hepatic impairment had higher systemic exposure to the drug than healthy subjects

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Weve seen a gradual increase in patients with the problem over the past year as the popularity of GLP-1 drugs has soared

Novel propargyl-linked bisubstrate analogues as tight-binding inhibitors for nicotinamide N-methyltransferase

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This rise reflects heightened awareness of the drugs potential risks and more patients coming forward with claims