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While they can be lifesaving in acute or emergency settings, repeated or long-term use is associated with well-documented steroid side effects affecting metabolic, immune, and musculoskeletal systems

These trials did not show clear advantages over placebo on standard PD scales, partly because sample sizes were small and placebo groups improved

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doi: 10.1016/j.expneurol.2023.114582

Understanding those differences is the first step in having a meaningful conversation with your healthcare provider