Published online January 14, 2026
In this comprehensive overview (see Methods and the search methodology in Supplementary Section 1), we aim to identify and describe pre-clinical, mechanistic and clinical studies on the effects of GLP-1RAs in cognitive and mental health disorders, and to provide a summary of available evidence and future perspectives
neuromuscular disorders that may cause muscle wasting, such as muscular dystrophy, spinal muscular atrophy or amyotrophic lateral sclerosis
In the ATTAIN-MAINTAIN trial, 205 patients taking tirzepatide and 171 patients taking semaglutide were randomized to take orforglipron or placebo (no active drug) daily for a year
Glucagon-like peptide-1 and glucagon-like peptide-1 receptor agonists in the treatment of type 2 diabetes
These vouchers followed agreements from Novo Nordisk and Lilly to cut prices on the drugs for Medicaid and Medicare patients