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Semaglutide slows stomach emptying to reduce appetitea mechanism that helps weight loss but can trigger constipation in roughly one in four patients
Patients with a history of serious hypersensitivity to tirzepatide or its excipients should not receive the medication, as this is a contraindication per the FDA prescribing information
2023 Jul 29;24(15):12180
Because semaglutide slows gastric emptying, oral contraceptives may stay in your stomach longer
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However, evidence regarding its use in individuals aged 65 years and older remains limited [12]
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