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Superimposing a tonic pharmacological brake on top of this feedback system creates competing signals, and it would be unsurprising if intestinal feedback partially normalized emptying over time even while the drug is present

When and how CBT for BED use GLP-1RAs CBT for BED, as detailed in a manual (Dalle Grave et al., 2024), integrates strategies and procedures from both CBT-E for eating disorders (Dalle Grave & Calugi, 2020

Any legitimate investigation of this compound should occur within properly authorized clinical research under appropriate oversight, and readers should consult qualified professionals and applicable regulations before making any decisions.

Understanding GLP-1s and their role GLP-1 is a hormone released in the gut in response to eating

The use of GLP-1 drugs for the management of diabetes is increasing

In support of this, ICV administration of GLP-1 in rats has been shown to attenuate the fasting-induced rise in NPY/AgRP expression and decreases fasting-induced inhibition of POMC/CART expression in the ARC (Seo et al., 2008)