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Clinical studies suggest that a significant proportion of weight lost during caloric restriction can come from lean tissue

Drugmakers are actively working to secure FDA approval for other clinical indications as well

Increasing fiber and magnesium for constipation

We constructed standardized experimental models encompassing murine full-thickness burn injuries [13], rat dermal incisional wounds [13], and rodent skeletal muscle contusion models (Figure S1)

Short-chain fatty acids (SCFAs), which are produced in the gut by specific microorganisms, possess anti-inflammatory properties and may augment insulin sensitivity [73]

All those involve some form of restriction