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Mounjaro, in particular, has shown promising results, with patients achieving up to 26.6% weight loss over 84 weeks

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This study, published in JAMA Ophthalmology , is often referenced as one of the first to highlight a potential association

Swart PJ, Hirano T, Kuipers ME, Ito Y, Smith C, Hashida M, et al

And its anabolic-related genes include fibroblast growth factor-21 (FGF21), SREBP-1c, fatty acid synthase (FAS), acetyl-CoA carboxylase (ACC-a), liver X receptor (LXR), suppressor of cytokine signaling-3 (SOCS-3), etc