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At the same time, antipsychotics demonstrate antioxidant effects.135136137138 One study group has consistently reported that initial SOD level in schizophrenia was lower than that in controls, and both typical and atypical antipsychotics significantly increase SOD level.72139140141 The improvement in the psychopathology of patients with schizophrenia has been correlated with the degree of change in SOD level

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Among these, -tocopherol is the best known and possesses the most antioxidant activity (Janero, 1991)