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It results from failure of expression of paternally inherited genes in the PWS region of chromosome 15

doi: 10.1210/en.2005-0972 148 ChanJLMunECStoynevaVMantzorosCSGoldfineAB

After removal, bile flows continuously into the small intestine rather than surging on demand

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Until thorough human research is done, any use of Dihexa should be regarded as highly experimental and risky