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In addition to Complex I inhibition in humans and animal models of temporal lobe epilepsy (TLE), the redox regulated TCA cycle enzymes aconitase and -ketoglutarate dehydrogenase have been shown to be inactivated following status epilepticus (SE) in rats (Malinska et al., 2010)

When to extend timeline Consider using beyond 30 days when: Peptide is very expensive (TB-500, pharmaceutical GLP-1s) You're close to finishing vial (only 2-3 doses remain) Peptide appears perfect (clear, no smell, stored optimally) You're using for non-critical purpose (anti-aging vs acute injury) Financial hardship makes wasting difficult Maximum extension: 45 days for most stable peptides (BPC-157, TB-500, semaglutide)

The rate of progress depends on consistency, as well as ongoing adjustments made under the supervision of a healthcare professional