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Conclusions The importance of incretin hormones on the regulation of glucose homeostasis through pancreatic and extra-pancreatic actions is well established

57 CoskunTSloopKWLoghinCAlsina-FernandezJUrvaSBokvistKBet al

Weight management in type 2 diabetes For type 2 diabetes patients who are overweight or obese (which describes the majority), GLP-1 medications address both the glycemic and the weight components of their disease

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Conversely, data from clinical trials have showed an increased risk of incident heart failure with DPP4 inhibitors compared to placebo

Canada has one of the highest obesity rates among developed nations, with approximately 27% of Canadian adults classified as obese according to Statistics Canada data