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Semaglutide has two amino acid substitutions compared to human GLP-1 (Aib(8), Arg(34)) and is derivatized at lysine 26

Author Contributions M.H

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Fu, X., Qu, L., Xu, H

As two independent reviewers searched the electronic PubMed/MEDLINE, Scielo, Embase and Lilacs databases using the either the Medical Subject Headings (MeSH) terms or keywords semaglutide or GLP-1RA, combined with inflammation or C-reactive protein (CRP) or cytokines, or using the term semaglutide with the randomised clinical trials filter, and the data were extracted