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Its activating a specific hormonal pathway

10.3389/ftox.2023.1264331 77 MannetjeA.SteenlandK.AttfieldM.BoffettaP.CheckowayH.DeKlerkN.et al (2002)

Hyperglycemia and impaired insulin signaling contribute to the accumulation of ROS, which increases the susceptibility of cells to ferroptosis via iron-dependent lipid damage mechanisms [45]

This phase 2 reaction makes molecules more water-soluble

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