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Dysregulated mTORC1 and TFEB signaling exacerbate these autophagic defects, prompting research into the use of autophagy modulators as potential therapeutic strategies [144, 146]

The National Emphysema Treatment Trial (NETT): Part II: lessons learned about lung volume reduction surgery

This combined effect on appetite and glucose metabolism drives significant reductions in body weight

Despite its importance, B12 deficiency is relatively common, especially among the elderly, vegans, and people with certain medical conditions

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Its small size allows cells in vital organs to absorb and collect it, which can disrupt cellular homeostasis and produce inflammatory responses (Min et al., 2023)