TRIUMPH Phase 3 Retatrutide Trials (NCT05929014 and related)
GLP-1 product information updated to highlight risk of severe acute pancreatitis The product information for all GLP-1 and dual GLP-1/GIP receptor agonists including semaglutide and tirzepatide has been updated to highlight the risk of severe acute pancreatitis, including rare reports of necrotising and fatal pancreatitis
The Journal of Steroid Biochemistry and Molecular Biology, 85 , 195-200
Metformin HCl No pharmacokinetic studies of metformin have been conducted in patients with hepatic impairment
Ji L, Hao S, Wang J, Zou J, Wang Y
Of note, two independent groups simultaneously reported in 2010 that IGF-1R undergoes nuclear translocation in human cancers, indicating that IGF-1R itself may act as a transcription factor [88,89]