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Westwood AJ, Beiser A, Decarli C, Harris TB, Chen TC, He XM, et al
10.1161/HYPERTENSIONAHA.112.195115
Headache, particularly at initiation Mild anxiety or restlessness with some compounds Nasal irritation (intranasal administration) Sleep disturbance if dosed too close to bedtime Rare: Mood changes or emotional lability Dihexa (PNB-0408, N-hexanoic-Tyr-Ile-(6) aminohexanoic amide) is a potent hepatocyte growth factor (HGF) receptor agonist originally developed at Washington State University
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One theoretical concern: because TB-500 promotes new blood vessel growth, some researchers question whether it could support tumor vasculature