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Reduction of Inflammation and Oxidative Stress : Melanocortin activation by Melanotan II leads to suppression of pro-inflammatory cytokines such as TNF- and IL-1, along with enhanced antioxidant enzyme activity

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Moreover, plasma from individuals with T2DM showed mild but significant elevations in ketone bodies , inversely associated with insulin resistance measured by the Lipoprotein Insulin Resistance Index (LP-IR)

The area under the receiver operating characteristic (ROC) curve (AUC) resulted from the average of the predicted probabilities extracted from the internal validations across the entire dataset