Based on early-phase clinical trial data including a Phase 2 study published in the New England Journal of Medicine (2023) retatrutide has demonstrated significant effects on appetite suppression and glucose regulation
Some research indicates GLP-1s may help with metabolic syndrome risks , such as high blood pressure and high cholesterol, which become more common in perimenopause
It belongs to a class of medications called GLP-1 receptor agonists, originally developed to treat type 2 diabetes
However, if a patient is found to have low positive titers of paraneoplastic antibodies and suspicion is low for an occult cancer (eg, no weight loss or early satiety), repeat confirmatory testing at another laboratory should be done before embarking on an extensive search for malignancy
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K.EggelsL.van RozenA