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Conclusions B12 injections are one of several prophylactic B12 options now available for those with altered gastric acidity and/or Intrinsic Factor

However, the peptide is degraded by the enzymes DPP-IV and neutral endopeptidase 24.11 (Holst, 2007)

For example, one study demonstrated that endocannabinoid-like lipids can directly bind to GLP-1 and increase its potency via conformational changes 78

Nat Commun (2023) 14(1):6772

Several studies have found that how long B12 remains in the system can depend on underlying factors such as tendencies towards developing certain diseases and lifestyle choices

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