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+ B12 is a water-soluble vitamin, which means the body excretes any excess in the urine, so the safety profile is very forgiving

& Borah, A

Figure 1 Patients with GSSD, which is classified as mild, moderate, or severe based on clinical symptoms, usually show disease onset symptoms during the neonatal period ( 2

Also, the mapping approach for transcriptomic data is based on the inclusion of highly transcribed genes and therefore is biased towards more abundant proteins, hence potentially missing lowly abundant proteins relevant for viral replication

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Thermo Fisher Scientific) and integrity-confirmed with the high-sensitivity NGS assay on AATI Fragment Analyzer (Agilent)