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If experiencing anaphylaxis, or a severe allergic reaction, we encourage you to seek immediate medical advice, whether that be through our practice or your physician

Additionally, repeated intramuscular injections can cause muscle fibrosis or nerve damage if improper technique is employed

However, it is important to keep in mind that CLE visualizes a basolateral (subepithelial) to apical (luminal) flux of a small molecule (fluorescein) of which the correlation to luminal to subepithelial passage of luminal compounds, which is hypothesized to trigger a mucosal immune response and symptoms, is still unclear

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Subcutaneous dosing offers more predictable pharmacokinetics but requires proper injection technique and cold-chain storage of reconstituted peptide