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Dosage and use At the beginning of therapy during the first two weeks after diagnosis 1 ml (one ampoule) B12 Ankermann Injekt 1,000 g is administered once or twice a week, which equals 1,000-2,000 g cyanocobalamin per week

J Dermatol Sci

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The SURMOUNT-1 trial reported -22.5% weight reduction at the 15 mg weekly dose across 72 weeks (PMID 35658024)

This allows for more efficient delivery and improved utilisation within the body

The pituitary ROI was centered at (MNI: x = 0 mm, y = 2 mm, z = 32 mm) [43] and expanded to cover nearby areas with high T1w image intensity (63 voxels, 0.50 mL)